Topicality. Diseases of the circulatory system continue to be the leading cause of death in the vast majority of economically developed countries. Every year, more than 7 million people die from coronary heart disease in the world, including almost 2 million Europeans. Myocardial infarction is the extreme degree of ischemic heart disease. In Ukraine, with 48,000 patients, 20% of patients die from acute myocardial infarction every year, while in European countries - 5%. In 2020, the mortality rate from MI was 26.3 per 100,000 population, increasing from 25.3 in 2019 [1].