EFFECT OF COORDINATION COMPOUND OF GERMANIUM WITH NICOTINIC ACID ON THE EXPRESSION OF MARKERS OF NERVOUS TISSUE DAMAGE IN RATS UNDER CONDITIONS OF CHRONIC ETHANOL CONSUMPTION
Introduction. Long-term alcohol consumption can lead to the development of oxidative stress, changes in the structure and functions of the brain [1], which disrupts the functioning of the body as a whole.
References
Virgolini, M. B., Pautassi, R.M. (2022). Converging mechanisms in ethanol neurotoxicity. William Slikker, Michael Aschner & Lucio G. Costa (ed.) Neurotoxicity of Drugs of Abuse (49-92). London: Elsevier Inc./ Academic Press. https://doi.org/10.1016/bs.ant.2022.06.002
Abdelhak, A., Foschi, M., Abu-Rumeileh, S., Yue, J. K., D’Anna, L., Huss, A., Oeckl, P., Ludolph, A. C., Kuhle., J., Petzold, A., Manley, G. T., Green, A. J., Otto M. & Tumani H. (2022). Blood GFAP as an emerging biomarker in brain and spinal cord disorders. Nature Reviews Neurology, (18), 158-172. https://doi.org/10.1038/s41582-021-00616-3
Wittekindt, M., Kaddatz, H., Joost, S., Staffeld, A., Bitar, Y., Kipp, M. & Flintrop L. (2022). Different Methods for Evaluating Microglial Activation Using Anti-Ionized Calcium-Binding Adaptor Protein-1 Immunohistochemistry in the Cuprizone Mode. Cells, 11(11), 1723. https://doi.org/10.3390/cells11111723
Yuan, A. & Nixon, A. R. (2021) Neurofilament Proteins as Biomarkers to Monitor Neurological Diseases and the Efficacy of Therapies. Frontiers in Neuroscience, (15), 689938. https://doi.org/10.3389/fnins.2021.689938
Narokha, V. Nizhenkovska, I. & Kuznetsova, O. (2022) Potential of Germanium-Based Compounds in Coronavirus Infection. Acta Pharmaceutica, (72), 245–258. https://doi.org/10.2478/acph-2022-0016
Narokha, V. (2016). The effect of different doses of coordination compounds of germanium with nicotinic acid on lipid peroxidation and comparative influence of coordination compounds of germanium with different bioligands on fatty acid spectrum of lipids of cardiomyocytes in. Ukrainian Scientific Medical Youth Journal, (2(95), 86-91. Retrieved from https://mmj.nmuofficial.com/index.php/journal/article/view/141