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Biology and Biotechnology

April 28, 2023; Seoul, South Korea: II International Scientific and Practical Conference «THEORETICAL AND PRACTICAL ASPECTS OF MODERN SCIENTIFIC RESEARCH»


LONG-CHAIN TRIPHENYLPHOSPHONIUM IONIC LIQUIDS AS ANTIBACTERIALS IN POTENTIAL POLYMICROBIAL INFECTIONS CAUSED BY STAPHYLOCOCCUS AUREUS AND ACINETOBACTER BAUMANNII STRAINS


DOI
https://doi.org/10.36074/logos-28.04.2023.26
Published
08.05.2023

Abstract

The study of potentional polymicrobial infections caused by antibiotic-resistant isolate strains of Acenitobacter baumannii and Staphylococcus aureus in terms of the search for effective antibacterials is the goal of this work.

References

  1. Miller DP, Wang Q, Weinberg A, Lamont RJ. (2018) Transcriptome analysis of Porphyromonas gingivalis and Acinetobacter baumannii in polymicrobial communities. Mol Oral Microbiol., 33(5), 364-377. doi:10.1111/omi.12238.
  2. Yo CH, Hsein YC, Wu YL. (2019) Clinical predictors and outcome impact of community-onset polymicrobial bloodstream infection. Int J Antimicrob Agents, 54(6), 716-722. doi:10.1016/j.ijantimicag.2019.09.015.
  3. Wang Y-C, Ku W-W, Yang Y-S, Kao C-C, Kang F-Y, Kuo S-C, Chiu C-H, Chen T-L, Wang F-D, Lee Y-T. (2020) Is Polymicrobial Bacteremia an Independent Risk Factor for Mortality in Acinetobacter baumannii Bacteremia? J. Clin. Med., 9(1), 153. https://doi.org/10.3390/jcm9010153.
  4. Batoni G, Maisetta G, Esin S. (2021) Therapeutic Potential of Antimicrobial Peptides in Polymicrobial Biofilm-Associated Infections. Int. J. Mol. Sci., 22(2), 482. https://doi.org/10.3390/ijms22020482.
  5. de Breij A, Riool M, Cordfunke RA. (2018) The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms. Sci Transl Med., 10(423):eaan4044. doi:10.1126/scitranslmed.aan4044.
  6. Shchelik IS, Gademann K. (2021) Thiol- and Disulfide-Containing Vancomycin Derivatives Against Bacterial Resistance and Biofilm Formation. ACS Med. Chem. Lett., 12, 1898–1904. https://pubs.acs.org/doi/10.1021/acsmedchemlett.1c00455.
  7. Picconi P, Hind C, Jamshidi S, Nahar K, Clifford M,. Wand ME, Sutton JM, Rahman KM. (2017) Triaryl Benzimidazoles as a New Class of Antibacterial Agents against Resistant Pathogenic Microorganisms. J. Med. Chem., 60(14), 6045–6059. https://doi.org/10.1021/acs.jmedchem.7b00108.
  8. Piatek M, O’Beirne C, Beato Z, Tacke M, Kavanagh K. (2023) Pseudomonas aeruginosa and Staphylococcus aureus Display Differential Proteomic Responses to the Silver(I) Compound, SBC3. Antibiotics, 12(2), 348. https://doi.org/10.3390/antibiotics12020348.
  9. Metelytsia LO, Hodyna DM, Semenyuta IV, Kovalishyn VV, Rogalsky SP, Derevianko KYu, Brovarets VS, Tetko IV. (2022) Theoretical and Experimental Studies of Phosphonium Ionic Liquids as Potential Antibacterials of MDR Acinetobacter baumannii. Antibiotics, 11(4), 491. https://doi.org/10.3390/antibiotics11040491.
  10. Bauer AW, Kirby WM, Sherris JC, Turck M. (1966) Antibiotic Susceptibility Testing by a Standardized Single Disk Method. Am. J. Clin. Pathol. 45, 493–496.
  11. Davies M, Nowotka M, Papadatos G, Dedman N, GaultonA, Atkinson F, Bellis L, Overington JP (2015) ChEMBL web services: streamlining access to drug discovery data and utilities. Nucleic Acids Research, 43, W612–W620. https://doi.org/10.1093/nar/gkv352.
  12. Waterhouse A, Bertoni M, Bienert S, Studer G, Tauriello G, Gumienny R, Heer FT, de Beer TAP, Rempfer C, Bordoli L, Lepore R, Schwede T. (2018) SWISS-MODEL: homology modelling of protein structures and complexes. Nucleic Acids Research, 46, W296–W303, https://doi.org/10.1093/nar/gky427.
  13. Sanner MF. (1999) Python: a programming language for software integration and development. J Mol Graph Model. 17(1), 57-61.
  14. https://www.chemaxon.com/ (accessed on March 28, 2023).
  15. Trott O, Olson AJ. (2010) AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J Comput Chem. 31(2), 455-61. doi: 10.1002/jcc.21334.
  16. https://discover.3ds.com/ (accessed on March 28, 2023).

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